Sustamine

Sustamine® is a dipeptide consisting of two amino acids (L-alanine and L-glutamine) connected by a peptide bond. Sustamine is stable in both heat and acids, is highly soluble, and can function as a source of glutamine in the body.

 

Best Sustamine

#1 Real Supplements Rated Best in 2020
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Unflavored, 400 Grams (40 Servings)
38 Reviews
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Unflavored, 400 Grams (40 Servings)
  • WHAT’s IN THE PRODUCT: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid supplies 100% enzymatically and fermented pharmaceutical grade dipeptide L-Alanyl L-Glutamine which delivers a massive 10g dosage per scoop.
  • WHAT NOT IN THE PRODUCT: There is NO Calories, NO Gluten, No GMO’s, NO Lactose, NO Soy Protein, NO Added-Sugar, NO Trans Fat, NO Aspartame, NO Fillers, NO Preservatives, NO Additives, NO Amino Spiking, NO Illegal Substances and NO Gimmicks
  • WHAT IT DOES FOR YOU: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid is physician formulated & designed for healthy Men or Women who are on-the-go professionals, athletes, students and competitors alike, who need and easy and quick dissolving L-Glutamine powder that tastes great and works even better to enhance their athletic training and physical recovery. Available in 3 delicious flavors, as well as, Unflavored…in 400g size…delivering 40 individual servings.
  • HOW IT WORKS: T.A.G. (Trans Alanyl Glutamine) di-peptide Amino Acid out performs regular L-Glutamine by bypassing regular digestion and absorbs quickly into the bloodstream for enhanced muscle growth, increase strength, prevent muscle loss and speed recovery by increasing serum amino acid levels leading to increase protein synthesis to help push your performance and physique to the next level. T.A.G. also works to support a healthier Immune Function.
  • QUALITY GUARANTEE: All products are made in a pharmaceutical FDA-Registered GMP manufacturing facility in the USA. All ingredients are sourced from the USA and are HPLC & FTIR lab tested for quality, purity and efficacy. We the manufacturer, provide all purchases with a No-Risk Warranty to make sure those made on the Metabolic Nutrition Storefront is one with clear conscious and your money is not going to waste. All purchases are covered with a No Questions Asked 30 Day Money Back Guarantee!
#2 Real Supplements Rated Best in 2020
Genius Electrolyte Powder – Natural Hydration Booster | Endurance Supplement with Electrolytes (Potassium, Magnesium, Zinc) - Sugar Free, Vegan, Keto Friendly Energy - Orange Fizz (Drink Mix), 30 Sv
885 Reviews
Genius Electrolyte Powder – Natural Hydration Booster | Endurance Supplement with Electrolytes (Potassium, Magnesium, Zinc) - Sugar Free, Vegan, Keto Friendly Energy - Orange Fizz (Drink Mix), 30 Sv
  • THE SMART SPORTS DRINK - Most of the leading sports drinks are packed with sugar. Genius Electrolyte powder contains absolutely no sugar, artificial flavoring, sweeteners, fillers, or dyes. This electrolyte supplement contains, chelated magnesium, potassium, zinc, organic citric acid , and other quality replenishing minerals.
  • CRAMP DEFENSE & MUSCLE RECOVERY - No other electrolyte tablet, packet or pill provides the same effectiveness against cramps & dehydration. With a full dose of potassium bicarbonate (comparable to potassium citrate) no other hydrator on the market helps you replenish like this. Use pre, post or intra workout for optimal recovery
  • PUSH YOUR LIMITS (The Smart Way) - When you need a low calorie, no sugar, option to boost your training, just add Genius to water. Not only are these electrolytes keto friendly they are 100% pure & simple trace minerals. This electrolyte drink doesn’t skimp out on quality. It is both made and manufactured in the USA within a GMP and FDA compliant facility. Third Party tested for potency and purity.
  • PARTY SMART - Genius Electrolytes is the smart recovery drink. The ultima replenisher , Genius Electrolytes restores and replenishes the body of its proper nutrients, hydrating you and getting you back to peak performance. Choose the Genius recovery hangover drink. Go out and thrive, plus feel your best the next morning!
#3 Real Supplements Rated Best in 2020
Metagenics Glutagenics® – Powerful Gastrointestinal Lining Support* | 60 servings
  • Supports a healthy intestinal lining, which is essential for proper digestion, immune function, and overall health*
  • Features the amino acid glutamine, which provides both a source of fuel and precursors for growth to the rapidly dividing cells of the intestinal lining*
  • Delivers a concentrated licorice extract that has been processed to remove glycyrrhizin, which has been associated with sodium and water retention*
  • Features a premium powder of decolorized inner leaf aloe to support a healthy intestinal lining*
  • This product is non-GMO, gluten-free, and vegetarian
#4 Real Supplements Rated Best in 2020
PEScience TruGlutamine, Unflavored, 30 Serving
  • Contains glutamine and alanine
  • Easy to mix with any flavor
  • Contains low sugar content
  • Supplies 30 servings
  • Contains no flavor
#5 Real Supplements Rated Best in 2020
Terra Origin Healthy Gut Digestive Support Supplement, Powder, Berry, 30 Servings, Includes L-Glutamine, Herbs, Antioxidants for Leaky Gut Support, Promotes Healthy Digestion
  • Balances the intestinal lining and relieves gastric distress. Builds and repairs the intestines and decreases intestinal permeability. Protects the gut mucosal structure and improves gut immune response. Protects the gut mucosal structure and improves gut immune response. Helps heal the stomach lining with anti-inflammatory and immune boosting properties.
  • Our Healthy Gut lets you do more of the things you love, and worry less about what you had to eat.
  • Contains vitamins and herbs proven by research to support the digestive system and improve gut lining, such as Glutamine and N-Acetyl Glucosamine.
  • Also contains an antioxidant mix to calm free radicals.
  • As always, our products reflect our high standards - we do not add in empty fillers or confusing preservatives.
#6 Real Supplements Rated Best in 2020
INNATE Response Formulas - GI Response, Powdered Digestive Blend to Support Gastrointestinal Health, 30 Servings (237 Grams)
19 Reviews
INNATE Response Formulas - GI Response, Powdered Digestive Blend to Support Gastrointestinal Health, 30 Servings (237 Grams)
  • SUPPORT YOUR GUT: Our easy-to-mix drink powder that blends 5 grams of L-glutamine, which may support optimal permeability of the intestinal barrier
  • BOTANICAL SUPPORT: Includes botanicals, marshmallow root and slippery elm bark
  • ONE SCOOP: Mix 1 scoop with of 8-10 oz of water or your favorite cold beverage daily
  • QUALITY ASSURED: Certified Glyphosate Residue Free, Certified B Corp and magnesium stearate free
  • WHERE NATURE AND SCIENCE MEET: Wellness is our natural state; that’s why we take a wholistic approach to health by crafting supplements to support your body’s needs
Sale#7 Real Supplements Rated Best in 2020
Optimum Nutrition L-Glutamine Muscle Recovery Capsules, 1000mg, 240 Count (Package May Vary)
  • 1000 milligram of pure l glutamine per 2 capsules
  • Most abundant amino acid in the body
  • Plays an important role in muscle protein development
  • During prolonged periods of intense exercise, glutamine levels may be depleted
  • Package may vary (120 count or 240 count)
Sale#8 Real Supplements Rated Best in 2020
Oxylent Sport 3-in-1 Performance Supplement Drink - Sugar-Free, Effervescent, Easy Absorption of Vitamins, Creatine Minerals, Natural Energy, Supports Stamina, Blueberry Burst Flavor, 15 Count
18 Reviews
Oxylent Sport 3-in-1 Performance Supplement Drink - Sugar-Free, Effervescent, Easy Absorption of Vitamins, Creatine Minerals, Natural Energy, Supports Stamina, Blueberry Burst Flavor, 15 Count
  • FOR THE NATURAL ATHLETE: Our formula contains cutting-edge ingredients that enhances your workout
  • AWARD WINNING: 2017 Delicious Living Supplement Award – Best New Sports Supplement
  • ENERGY PERFORMANCE: Citrulline Malate and B vitamins enhance energy and blood flow
  • Oxylent Ad Setup Oxylent Ad Setup 100% 11 STAMINA PERFORMANCE: Sustaminecombines Glutamine & Alanine to sustain energy for longer workouts Screen reader support enabled. STAMINA PERFORMANCE: Sustaminecombines Glutamine & Alanine to sustain energy for longer workouts
  • RECOVERY: Antioxidants, super fruits, amino acids, vitamin C & D help reduce the time of recovery
#9 Real Supplements Rated Best in 2020
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Fruit Punch, 400 Grams (40 Servings)
14 Reviews
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Fruit Punch, 400 Grams (40 Servings)
  • WHAT’s IN THE PRODUCT: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid supplies 100% enzymatically and fermented pharmaceutical grade dipeptide L-Alanyl L-Glutamine which delivers a massive 10g dosage per scoop.
  • WHAT NOT IN THE PRODUCT: There is NO Calories, NO Gluten, No GMO’s, NO Lactose, NO Soy Protein, NO Added-Sugar, NO Trans Fat, NO Aspartame, NO Fillers, NO Preservatives, NO Additives, NO Amino Spiking, NO Illegal Substances and NO Gimmicks
  • WHAT IT DOES FOR YOU: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid is physician formulated & designed for healthy Men or Women who are on-the-go professionals, athletes, students and competitors alike, who need and easy and quick dissolving L-Glutamine powder that tastes great and works even better to enhance their athletic training and physical recovery. Available in 3 delicious flavors, as well as, Unflavored…in 400g size…delivering 40 individual servings.
  • HOW IT WORKS: T.A.G. (Trans Alanyl Glutamine) di-peptide Amino Acid out performs regular L-Glutamine by bypassing regular digestion and absorbs quickly into the bloodstream for enhanced muscle growth, increase strength, prevent muscle loss and speed recovery by increasing serum amino acid levels leading to increase protein synthesis to help push your performance and physique to the next level. T.A.G. also works to support a healthier Immune Function.
  • QUALITY GUARANTEE: All products are made in a pharmaceutical FDA-Registered GMP manufacturing facility in the USA. All ingredients are sourced from the USA and are HPLC & FTIR lab tested for quality, purity and efficacy. We the manufacturer, provide all purchases with a No-Risk Warranty to make sure those made on the Metabolic Nutrition Storefront is one with clear conscious and your money is not going to waste. All purchases are covered with a No Questions Asked 30 Day Money Back Guarantee!
#10 Real Supplements Rated Best in 2020
BulkSupplements.com L-Glutamine (1 Kilogram - 2.2 lbs - 1000 Servings)
3,174 Reviews
BulkSupplements.com L-Glutamine (1 Kilogram - 2.2 lbs - 1000 Servings)
  • Help boost athletic endurance and aid exercise recovery*
  • Fortify immune function*
  • Support healthy metabolic function*
  • Promote digestive and gut health*
  • Contribute to overall health and wellness*
#11 Real Supplements Rated Best in 2020
MP Essentials 100% Pure Glutamine Powder, Muscle Growth and Recovery, L-Glutamine Powder, Promotes Recovery after Intense Exercise, Helps Repair Muscles, MusclePharm, 300 g, 60 Servings
275 Reviews
MP Essentials 100% Pure Glutamine Powder, Muscle Growth and Recovery, L-Glutamine Powder, Promotes Recovery after Intense Exercise, Helps Repair Muscles, MusclePharm, 300 g, 60 Servings
  • HELPS BUILD, REPAIR, AND PROTECT MUSCLES: MusclePharm 100% Pure Glutamine Powder supplements the body with the amino acid glutamine, which helps build, repair, and protect muscles from damage.
  • PROMOTES RECOVERY AFTER INTENSE EXERCISE: Glutamine has been shown to promote recovery after intense workouts and physical exercise. Athletes and workout professionals have used L-glutamine powder as a safe supplement for years.
  • SUPPORTS GUT AND IMMUNE FUNCTION: Intense workouts and physical activity can deplete glutamine, which is critical for proper gut and immune system functioning. The introduction of 5 grams of L-glutamine improves gut and immune function.
  • BANNED-SUBSTANCE TESTED: We care about the products you put into your body. MusclePharm 100% Pure Glutamine Powder is banned-substance tested and certified by Informed-Choice.
  • 100% MONEY-BACK GUARANTEE: All MusclePharm products are backed by a 30-day full money-back guarantee.
#12 Real Supplements Rated Best in 2020
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Blue Raspberry, 400 Grams (40 Servings)
  • WHAT’s IN THE PRODUCT: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid supplies 100% enzymatically and fermented pharmaceutical grade dipeptide L-Alanyl L-Glutamine which delivers a massive 10g dosage per scoop.
  • WHAT NOT IN THE PRODUCT: There is NO Calories, NO Gluten, No GMO’s, NO Lactose, NO Soy Protein, NO Added-Sugar, NO Trans Fat, NO Aspartame, NO Fillers, NO Preservatives, NO Additives, NO Amino Spiking, NO Illegal Substances and NO Gimmicks
  • WHAT IT DOES FOR YOU: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid is physician formulated & designed for healthy Men or Women who are on-the-go professionals, athletes, students and competitors alike, who need and easy and quick dissolving L-Glutamine powder that tastes great and works even better to enhance their athletic training and physical recovery. Available in 3 delicious flavors, as well as, Unflavored…in 400g size…delivering 40 individual servings.
  • HOW IT WORKS: T.A.G. (Trans Alanyl Glutamine) di-peptide Amino Acid out performs regular L-Glutamine by bypassing regular digestion and absorbs quickly into the bloodstream for enhanced muscle growth, increase strength, prevent muscle loss and speed recovery by increasing serum amino acid levels leading to increase protein synthesis to help push your performance and physique to the next level. T.A.G. also works to support a healthier Immune Function.
  • QUALITY GUARANTEE: All products are made in a pharmaceutical FDA-Registered GMP manufacturing facility in the USA. All ingredients are sourced from the USA and are HPLC & FTIR lab tested for quality, purity and efficacy. We the manufacturer, provide all purchases with a No-Risk Warranty to make sure those made on the Metabolic Nutrition Storefront is one with clear conscious and your money is not going to waste. All purchases are covered with a No Questions Asked 30 Day Money Back Guarantee!
#13 Real Supplements Rated Best in 2020
NF Sports Hydrate 2.0 – an All-Natural Daily Hydration Mix Made formulated with Electrolyte and Sustamine® to Amplify Hydration and Increase Performance. (Citrus Zest)
  • HELPS YOU PERFORM FOR A LONGER PERIOD OF TIME | When doing a high intensity workout, this all-natural hydration mix will help you perform for a longer period of time. With a combined formula of coconut water powder and Sustamine this mix helps the body rehydrate, replenish, and recover.
  • REGULATES YOUR BODY TEMPERATURE AND LUBRICATES YOUR JOINTS | Sustamine is a revolutionary dipeptide form of L-Glutamine that supplies a combination of pure L-Glutamine (an amino acid for stimulating muscle protein synthesis) and L-Alanine (an amino acid needed for rebuilding glycogen stores). This process allows protein to be absorbed quickly, helping you regulate your body temp and perform better.
  • TRANSPORTS NUTRIENTS TO GIVE YOU ENERGY AND KEEP YOU HEALTHY | When you hydrate better your whole body reaps the rewards. By keeping up your electrolyte levels during high intensity workouts you ensure that you are transporting the nutrients your body needs everywhere, keeping your energy levels up.
  • REPLENISH VITAL WASTED ELECTROLYTES AND MINERALS | It’s no secret that when you train you expend important minerals and electrolytes. This mix is specifically designed to replenish these minerals and electrolytes throughout your entire workout keeping you going.
  • HELPS INCREASE THE ABSORPTION RATE WHEN CONSUMING WATER | Coconut Water Powder helps your body stay hydrated and absorb the electrolytes and hydration your body needs during workouts. With potassium, calcium, magnesium, phosphorous, and sodium to help balance electrolyte levels and prevent dehydration.
Sale#14 Real Supplements Rated Best in 2020
ZymaDerm for Molluscum, Natural, Fast, Gentle, Painless – FDA Registered, Made in USA, 13 milliliter
  • Plant-based formulation containing essential oils aids in the elimination of molluscum papules to restore clear skin.
  • Parents can painlessly apply ZymaDerm with glass applicator. One bottle can treat 60 papules, twice a day, for one month.
  • Doctor-developed. Two published clinical trials show ZymaDerm’s core ingredients have an 84% success rate of clearing molluscum symptoms.
  • 86% of doctors surveyed rated the formulation’s key ingredients effective at treating the symptoms of molluscum.
  • Made in the USA in an FDA-registered facility. ZymaDerm is FDA-registered: NDC# 69163-4136-1.
#15 Real Supplements Rated Best in 2020
Genius Consciousness - Super Nootropic Brain Booster Supplement - Enhance Focus, Boost Concentration & Improve Memory | Mind Enhancement with Alpha GPC & Lions Mane Mushroom for Neuro Energy & IQ
  • HEIGHTENED MENTAL CLARITY, FOCUS & COGNITIVE PERFORMANCE - Reduce brain fog and clear the cobwebs holding you back from achieving limitless status! Find creativity and free your thoughts with modern science (see product description below for scientific breakdown)
  • CLINICALLY PROVEN, TRADEMARKED INGREDIENTS - Doctor formulated & 3rd party tested, Genius doesn't leave quality up to chance. Highlights from our extra strength formula include 100mg of Phosphatidylserine, 1000mg of Acetyl L Carnitine HCL and 500mg of L-Tyrosine for higher level thought processing, dopamine production and nerve support
  • NO PRESCRIPTION REQUIRED - Unlike some synthetic smart drugs, Consciousness provides a natural alternative to unproven compounds! Made with all-natural, scientifically proven ingredients; Consciousness truly does support brain health
  • FAST-ACTING ENERGY & MOOD SUPPORT - Dyamine, Neurofactor and Natural Caffeine ignite neurons to leave you feeling bullet proof! Find your neuro peak and leave anxiety behind with SAFE stimulants (Packaging may slightly vary).
Sale#16 Real Supplements Rated Best in 2020
Jarrow Formulas L-Glutamine Powder, Supports Muscle Tissue, 2 g per Serving, 35.3 Oz
  • L-Glutamine the most abundant amino acid in the human body is involved in many metabolic processes, including the synthesis and protection of muscle tissue, the production of glycogen, and immune support during periods of immune and muscular stress
  • Jarrow Formulas
Sale#17 Real Supplements Rated Best in 2020
Atrantil (90 Clear Caps): Bloating, Abdominal Discomfort, Change in Bowel Habits, and Everyday Digestive Health
633 Reviews
Atrantil (90 Clear Caps): Bloating, Abdominal Discomfort, Change in Bowel Habits, and Everyday Digestive Health
  • Do YOU BLOAT AFTER EATING CERTAIN FOODS? If yes, then you should try Atrantil
  • TARGETED TREATMENT - Atrantil targets the small bowel to provide relief where it is needed. Where digestive issues begin
  • GASTROENTEROLOGIST INNOVATION - Atrantil was developed by a board certified gastroenterologist for treatment of digestive issues
Sale#18 Real Supplements Rated Best in 2020
Havasu Nutrition Extra Strength L Arginine - 1200mg Nitric Oxide Supplement for Muscle Growth, Vascularity and Energy - L-Citrulline & Essential Amino Acids to Support Physical Endurance, 60 Capsules
5,104 Reviews
Havasu Nutrition Extra Strength L Arginine - 1200mg Nitric Oxide Supplement for Muscle Growth, Vascularity and Energy - L-Citrulline & Essential Amino Acids to Support Physical Endurance, 60 Capsules
  • NITRIC OXIDE IN A NUTSHELL. Nitric oxide may sound like something a mad scientist would create, but it's actually a naturally occurring molecule your body needs! Automatically, your body converts the amino acid Arginine, found in our L-Arginine and L-Citrulline ingredient combination, into a benefit-packed nitric oxide.
  • A TINY MOLECULE WITH A BIG JOB. We know just how important it is to take care of your vital organs, which is why our arginine supplement is specially formulated for better overall blood circulation.* Each nitric oxide molecule works to relax your blood vessels so that oxygen can flow more freely throughout your body.*
  • SAY YES TO "NO2": Our customers can't get enough of our nitric oxide supplements, join them in saying yes to all-day energy, increased physical endurance, better post-workout muscle recovery, and overall improved blood circulation from head to toe.*
  • MUSCLE BUILDER FOR MEN AND WOMEN. With age and stress, we know it can be hard to get past your fitness plateau. Our nitric oxide booster supplements can help give you the endurance you need to workout harder and longer, so that you can see improved muscle growth and vascularity quicker.*
  • BENEFITS BEYOND THE GYM. Our nitrous oxide supplements for men and women, will provide you with all of the full-body benefits that increased oxygen has to offer. Our supplements are formulated with the most effective natural ingredients at the perfect doses because your overall health and wellness is our priority.
#19 Real Supplements Rated Best in 2020
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Green Apple, 400 Grams (40 Servings)
8 Reviews
Metabolic Nutrition, TAG, Trans Alanyl Glutamine, 100% L-Glutamine Peptide Powder, Pre Intra Post Workout Supplement, Green Apple, 400 Grams (40 Servings)
  • WHAT’s IN THE PRODUCT: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid supplies 100% enzymatically and fermented pharmaceutical grade dipeptide L-Alanyl L-Glutamine which delivers a massive 10g dosage per scoop.
  • WHAT NOT IN THE PRODUCT: There is NO Calories, NO Gluten, No GMO’s, NO Lactose, NO Soy Protein, NO Added-Sugar, NO Trans Fat, NO Aspartame, NO Fillers, NO Preservatives, NO Additives, NO Amino Spiking, NO Illegal Substances and NO Gimmicks
  • WHAT IT DOES FOR YOU: T.A.G. (Trans Alanyl Glutamine) Targeted Muscle Recovery Amino Acid is physician formulated & designed for healthy Men or Women who are on-the-go professionals, athletes, students and competitors alike, who need and easy and quick dissolving L-Glutamine powder that tastes great and works even better to enhance their athletic training and physical recovery. Available in 3 delicious flavors, as well as, Unflavored…in 400g size…delivering 40 individual servings.
  • HOW IT WORKS: T.A.G. (Trans Alanyl Glutamine) di-peptide Amino Acid out performs regular L-Glutamine by bypassing regular digestion and absorbs quickly into the bloodstream for enhanced muscle growth, increase strength, prevent muscle loss and speed recovery by increasing serum amino acid levels leading to increase protein synthesis to help push your performance and physique to the next level. T.A.G. also works to support a healthier Immune Function.
  • QUALITY GUARANTEE: All products are made in a pharmaceutical FDA-Registered GMP manufacturing facility in the USA. All ingredients are sourced from the USA and are HPLC & FTIR lab tested for quality, purity and efficacy. We the manufacturer, provide all purchases with a No-Risk Warranty to make sure those made on the Metabolic Nutrition Storefront is one with clear conscious and your money is not going to waste. All purchases are covered with a No Questions Asked 30 Day Money Back Guarantee!
#20 Real Supplements Rated Best in 2020
Pure Advantage Glutamine Peptides BCAAs Supplement, 1.1 Pound
  • Pure Advantage Glutamine Peptides contain high levels of glutamine-rich peptides isolated from whey proteins to deliver the essential amino acid L-Glutamine in a soluble and highly bioavailable form
  • Amino acids, also known as BCAAs are the building blocks of muscle; BCAA supplements like Glutamine make sure your body has all it needs to do the work day in and day out
  • Our Glutamine Peptides provide an enhanced form of L-Glutamin to help increase muscle growth and recovery
  • Glutamine Peptides are the most anticipated amino acid supplement on the market and far superior to standard L-Glutamine; structured Peptides are absorbed faster, utilized better, and provides the body with the greatest effects from glutamine BCAA supplementation
  • Simple to use, just mix 5 grams into your favorite meal replacement shake or protein smoothie; 100 servings per container

Best Reasons to Consider Sustamine

Sustamine® is a dipeptide consisting of two amino acids (L-alanine and L-glutamine) connected by a peptide bond. Sustamine is stable in both heat and acids, is highly soluble, and can function as a source of glutamine in the body.

Sustamine® is an ingredient that may assist with hydration and support exercise performance* Ultra-pure, clinically tested, Sustamine® is produced through a patented fermentation method to create a unique dipeptide that is more easily absorbed by the body than complex protein molecules.

Everyone has heard of glutamine, yet it’s supplement cousin, L-Alanyl-L-Glutamine, may be less familiar to many of you. Even its snappier name, Sustamine™ – is it just me, or does that sounds like a ’90s grunge band? – may not ring a bell. However, a growing body of science is causing quite a chorus of support for this unique dipeptide.

Alanylglutamine is a stable and soluble delivery form of glutamine, but are there benefits to consuming this dipeptide that go beyond what you’d expect from a glutamine and alanine supplement? I’m here to sort through the science and let you know.

What Is It?
Before diving into alanylglutamine, let’s do a brief review of its constituent parts, L-alanine and L-glutamine.

Only then will you understand why this dipeptide could help any serious athlete or physique trainer reach their goals.

Alanine is categorized as a non-essential amino acid, whereas glutamine is conditionally essential.

Yet both are vitally involved in the exchange of nitrogen between tissues and the production and/or storage of glucose.

Both affect hydration. Both are significantly affected by strenuous exercise and other forms of physiological stress.

They seem like a match made in supplement heaven.

The functions of alanine and glutamine don’t just occur in parallel; they’re incredibly synergistic:

Alanine is the most important amino acid involved in carrying nitrogen from muscle to the liver. Once there, the amino acid’s carbon skeleton can be converted to glucose as part of a process called the glucose-alanine cycle.
Glutamine is the primary transporter between cells of nitrogen derived from protein breakdown, and it stimulates glucose-like peptide-1 (GLP-1). So glutamine helps maintain blood glucose levels and supports glycogen synthesis.
Both amino acids also improve hydration in synergistic ways. Alanine appears to influence cellular hydration and volume by raising intracellular potassium concentrations, thereby drawing water into the cell. Glutamine helps maintain your body’s overall acid-base balance, because the ammonia that’s cleaved from the amino acid and delivered to the kidneys affects water transport.

In response to strenuous exercise or other forms of physiological stress, both amino acids are released from muscle in significant concentrations. If muscle concentrations of these amino acids aren’t restored, exercise performance and recovery – not to mention immune function, muscle growth and a host of other biological functions – can suffer.

Put it all together, and it’s not hard to see how any bodybuilder or athlete could benefit from taking alanine and glutamine together.

Which bring us back to L-Alanyl-L-Glutamine. Unlike a whole protein that contains peptide fractions of all sizes – with some having thousands of peptide bonds – alanylglutamine contains just one peptide bond, linking L-alanine and L-glutamine.

This single peptide fragment is called a dipeptide. (If there were a third amino acid added to this chemical, it’d be called a tripeptide. Protein fractions with more than three joined amino acids are referred to as oligopeptides.)

The benefit of consuming a dipeptide versus a mixture of its two free-form amino acids is largely a matter of stability, solubility and absorption efficiency. Specifically, whereas L-glutamine is rapidly degraded to ammonia when put into solution and is poorly soluble, alanylglutamine is incredibly soluble.

Some studies suggest that it may remain stable for more than five years! And whereas free amino acids compete for uptake via highly selective amino acid transporters, dipeptides are more efficiently absorbed via minimally selective transporters, called PEPT1 transporters.

Think of amino acid transporters as selective “bouncers” that who only let A-listers into their club, one at a time. PEPT1 transporters are “bouncers” who don’t care who enters, so long as they show up in pairs or in groups of three. Because of the easier access, blood amino acid concentrations can rise faster when di- and tri-peptides are consumed versus free amino acids.

What Does It Do?
In animal models, alanylglutamine infusion has been reported to increase nitrogen retention and weight gain; decrease muscle and whole-body protein breakdown and leucine oxidation; increase gut integrity, function and circulation; and provide support against tissue damage.

Unfortunately, few human studies have looked at alanylglutamine consumed orally rather than clinically. Drs. Roger Harris and Jay Hoffman did surmise that blood glutamine concentrations were almost 60 percent higher when subjects drank a beverage containing alanylglutamine rather than a free-form L-glutamine. Even more impressive, total plasma glutamine concentrations were almost 126% higher in response to alanylglutamine.

This and other data seems to indicate that alanine and glutamine concentrations in the blood rise significantly in response to oral alanylglutamine supplementation, and that the resulting L-glutamine is preferentially used to synthesize l-citrulline and l-arginine.

Interestingly enough, chronic ingestion of alanylglutamine appears to significantly increase muscle glutamine concentrations more than chronic L-glutamine supplementation; however, no difference in muscle glutamine stores has been reported in response to acute immediately post-exercise with either the free or dipeptide form of glutamine.

It has also been reported that chronic supplementation of either the dipeptide or equal doses of free L-alanine and L-glutamine post-exercise, resulted in no significant differences for plasma glutamine, inflammatory response, or antioxidative capacity.

Though not universal, much of the research suggests equivocal results between the use of the dipeptide versus its constituent free amino acids.

What are the performance and physique applications?
Adding alanylglutamine to a rehydration solution is significantly more effective at increasing water and electrolyte absorption than consuming either a glutamine- or glucose-containing solution.

In a study by Hoffman and associates, the researchers concluded that the increase in performance that they observed in college kids cycling to exhaustion was likely due to an increase in water and electrolyte absorption after taking a Sustamine-containing solution. Ingestion of a Sustamine-containing solution delayed the onset of fatigue under mild dehydration by almost 190%, compared to dehydrated conditions.

Hoffman’s team has also presented evidence that 1 g of alanylglutamine per 500 mL of water maintains athletic skill performance and visual reaction time better than water only Division I female athletes who became dehydrated and then drank a solution. Doubling the dose of the dipeptide per 500 mL of water decreased fatigue but did not improve performance or reaction time.

Though no human studies have looked at whether oral alanylglutamine promotes muscle hypertrophy or strength, it seems likely that such a beneficial effect would be observed under conditions of high training volumes, very low carb intake, poor hydration, or some combination of the three.

What’s the bottom line?
Though the research on oral alanylglutamine and its effects on performance and body composition remains in its infancy, the early data looks very promising.

Its role in sparing muscle protein, supporting endurance or high-intensity training performance and recovery, supporting exercise in the heat, promoting hydration and healthy immune system function, and possibly serving as a synergist during low-carb dieting all make alanylglutamine a powerful active ingredient to consider adding to your supplement toolbox.

 


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